گزارش یک مورد کارسینوم مدولاری تیروئید و کارسینوم مجرایی پستان بطور همزمان

  The patient is a 49 year-old woman, a mother of four with enlarging thyroid gland for the past 15 years. Thyroid scan showed multinodular goiter. Thyroid hunction tests were in the range of normal. Fine needle aspiration of the thyroid was unsatisfactory. In the thyroid physical exam bilateral multiple and movable lymphadenopathies were detected on the anterior cervial chain.The thyroid was hard and nontender and nodular on population (CEA=400 ng/ml,calcitonin=1100 pg/ml).   A relatively fixed and non-tender mass measuring 1 × 1.5cm was felt in the superior-external lobe of the right breast this mass was present from eight months prior to the time of presentation.There was neither skin change nor nipple discharge. Excisional biopsy of the mass revealed infiltrating ductal carcinoma of the breast.   Modified radical mastectomy was subsequently performed.The patient then was prepared for thyroid surgery. Total thyroidectomy and modified neck dissection were carried out when the frozen section reportes malignant which was then confirmed to be medullary carcinoma of the thyroid gland.